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Transplantation of mouse embryonic stem cell-derived oligodendrocytes in the murine model of globoid cell leukodystrophy
INTRODUCTION: Globoid cell leukodystrophy (GLD) is a severe disorder of the central and peripheral nervous system caused by the absence of galactocerebrosidase (GALC) activity. Cell-based therapies are highly promising strategies for GLD. In this study, G-Olig2 mouse embryonic stem cells (ESCs) were...
Autores principales: | Kuai, Xiao Ling, Ni, Run Zhou, Zhou, Guo Xiong, Mao, Zheng Biao, Zhang, Jian Feng, Yi, Nan, Liu, Zhao Xiu, Shao, Nan, Ni, Wen Kai, Wang, Zhi Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413525/ https://www.ncbi.nlm.nih.gov/pubmed/25888852 http://dx.doi.org/10.1186/s13287-015-0024-2 |
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