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Fungal artificial chromosomes for mining of the fungal secondary metabolome

BACKGROUND: With thousands of fungal genomes being sequenced, each genome containing up to 70 secondary metabolite (SM) clusters 30–80 kb in size, breakthrough techniques are needed to characterize this SM wealth. RESULTS: Here we describe a novel system-level methodology for unbiased cloning of int...

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Detalles Bibliográficos
Autores principales: Bok, Jin Woo, Ye, Rosa, Clevenger, Kenneth D, Mead, David, Wagner, Megan, Krerowicz, Amanda, Albright, Jessica C, Goering, Anthony W, Thomas, Paul M, Kelleher, Neil L, Keller, Nancy P, Wu, Chengcang C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413528/
https://www.ncbi.nlm.nih.gov/pubmed/25925221
http://dx.doi.org/10.1186/s12864-015-1561-x