Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance

Resistance to treatment with anticancer drugs is a significant obstacle and a fundamental cause of therapeutic failure in cancer therapy. Functional doxorubicin (DOX) nanoparticles for targeted delivery of the classical cytotoxic anticancer drug DOX to tumor cells, using folate-terminated polyrotaxa...

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Detalles Bibliográficos
Autores principales: Wang, He, Yin, Henghui, Yan, Fengjiao, Sun, Mingna, Du, Lingran, Peng, Wei, Li, Qiuli, Feng, Yinghong, Zhou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413620/
https://www.ncbi.nlm.nih.gov/pubmed/25605018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413620/
https://www.ncbi.nlm.nih.gov/pubmed/25605018

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