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miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy

The present study identified miR-638 as one of the most significantly overexpressed miRNAs in metastatic lesions of melanomas compared with primary melanomas. miR-638 enhanced the tumorigenic properties of melanoma cells in vitro and lung colonization in vivo. mRNA expression profiling identified ne...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Animesh, Schmitz, Ulf, Raatz, Yvonne, Schönherr, Madeleine, Kottek, Tina, Schauer, Marianne, Franz, Sandra, Saalbach, Anja, Anderegg, Ulf, Wolkenhauer, Olaf, Schadendorf, Dirk, Simon, Jan C., Magin, Thomas, Vera, Julio, Kunz, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413631/
https://www.ncbi.nlm.nih.gov/pubmed/25650662