Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway

Slit2 is often overexpressed in cancers. Slit2 is a secreted protein that binds to Roundabout (Robo) receptors to regulate cell growth and migration. Here, we employed several complementary mouse models of intestinal cancers, including the Slit2 transgenic mice, the Apc(Min/+) spontaneous intestinal...

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Detalles Bibliográficos
Autores principales: Zhang, Qian-Qian, Zhou, Da-lei, Lei, Yan, Zheng, Li, Chen, Sheng-Xia, Gou, Hong-Ju, Gu, Qu-Liang, He, Xiao-Dong, Lan, Tian, Qi, Cui-Ling, Li, Jiang-Chao, Ding, Yan-Qing, Qiao, Liang, Wang, Li-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413642/
https://www.ncbi.nlm.nih.gov/pubmed/25605242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413642/
https://www.ncbi.nlm.nih.gov/pubmed/25605242

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