MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A

To assess the role of microRNAs (miR) in hepatocellular carcinoma (HCC), we performed comprehensive microRNA expression profiling using HCC cell lines and identified miR-93 as a novel target associated with HCC. We further verified miR-93 expression levels in advanced HCC tumors (n=47) by a direct P...

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Detalles Bibliográficos
Autores principales: Ohta, Katsuya, Hoshino, Hiromitsu, Wang, Jinhua, Ono, Shigeshi, Iida, Yuuki, Hata, Keisuke, Huang, Sharon K., Colquhoun, Steven, Hoon, Dave S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413648/
https://www.ncbi.nlm.nih.gov/pubmed/25633810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413648/
https://www.ncbi.nlm.nih.gov/pubmed/25633810

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