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MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A
To assess the role of microRNAs (miR) in hepatocellular carcinoma (HCC), we performed comprehensive microRNA expression profiling using HCC cell lines and identified miR-93 as a novel target associated with HCC. We further verified miR-93 expression levels in advanced HCC tumors (n=47) by a direct P...
Autores principales: | Ohta, Katsuya, Hoshino, Hiromitsu, Wang, Jinhua, Ono, Shigeshi, Iida, Yuuki, Hata, Keisuke, Huang, Sharon K., Colquhoun, Steven, Hoon, Dave S. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413648/ https://www.ncbi.nlm.nih.gov/pubmed/25633810 |
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