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Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer
The current understanding of the molecular mechanisms that lead to cancer is not sufficient to explain the loss or gain of function in proteins related to tumorigenic processes. Among them, more than 100 oncogenes, 20–30 tumor-suppressor genes, and hundreds of genes participating in DNA repair and r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413674/ https://www.ncbi.nlm.nih.gov/pubmed/25973395 http://dx.doi.org/10.3389/fonc.2015.00097 |