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Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration

Transcriptional expression of CXCR3 and CCR5 cognate chemokines correlate with CD8(+) T-cell infiltration and prolonged survival in colorectal cancer (CRC). These findings were derived mainly from paraffin embedded tissues; thus little is known about the secretion pattern of CD8(+) T-cell targeting...

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Detalles Bibliográficos
Autores principales: Zumwalt, Timothy J., Arnold, Mildred, Goel, Ajay, Richard Boland, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413778/
https://www.ncbi.nlm.nih.gov/pubmed/25671296