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Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration
Transcriptional expression of CXCR3 and CCR5 cognate chemokines correlate with CD8(+) T-cell infiltration and prolonged survival in colorectal cancer (CRC). These findings were derived mainly from paraffin embedded tissues; thus little is known about the secretion pattern of CD8(+) T-cell targeting...
Autores principales: | Zumwalt, Timothy J., Arnold, Mildred, Goel, Ajay, Richard Boland, C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413778/ https://www.ncbi.nlm.nih.gov/pubmed/25671296 |
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