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Analysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults

BACKGROUND: Clefts of the lip, alveolus, and palate (CLPs) rank among the most frequent and significant congenital malformations. Leu10Pro and Arg25Pro polymorphisms in the precursor region and Thr263Ile polymorphism in the prodomain of the transforming growth factor β1 (TGF-β1) gene have proved to...

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Detalles Bibliográficos
Autores principales: Stoll, Christian, Mengsteab, Senait, Stoll, Doris, Riediger, Dieter, Gressner, Axel M, Weiskirchen, Ralf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC441379/
https://www.ncbi.nlm.nih.gov/pubmed/15212689
http://dx.doi.org/10.1186/1471-2350-5-15