Cargando…
Of LAP, CUPS, and DRibbles – Unconventional Use of Autophagy Proteins for MHC Restricted Antigen Presentation
Macroautophagy delivers cytoplasmic constituents for lysosomal degradation. Because MHC class II molecules are loaded with lysosomal products for CD4(+) T-cell stimulation, macroautophagy supports intracellular antigen processing onto MHC class II molecules. The molecular machinery of macroautophagy...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413810/ https://www.ncbi.nlm.nih.gov/pubmed/25972871 http://dx.doi.org/10.3389/fimmu.2015.00200 |