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Apigenin Attenuates Atherogenesis through Inducing Macrophage Apoptosis via Inhibition of AKT Ser473 Phosphorylation and Downregulation of Plasminogen Activator Inhibitor-2

Macrophage survival is believed to be a contributing factor in the development of early atherosclerotic lesions. Dysregulated apoptosis of macrophages is involved in the inflammatory process of atherogenesis. Apigenin is a flavonoid that possesses various clinically relevant properties such as anti-...

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Detalles Bibliográficos
Autores principales: Zeng, Ping, Liu, Bin, Wang, Qun, Fan, Qin, Diao, Jian-Xin, Tang, Jing, Fu, Xiu-Qiong, Sun, Xue-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413885/
https://www.ncbi.nlm.nih.gov/pubmed/25960827
http://dx.doi.org/10.1155/2015/379538