Defining novel parameters for the optimal priming and expansion of minor histocompatibility antigen-specific T cells in culture

BACKGROUND: Adoptive transfer of minor histocompatibility antigen (MiHA)-specific T cells is a promising therapy for patients with hematological cancers. However, the efficacy of the transferred cells is hampered by the acquisition of terminal effector differentiation and exhaustion features during...

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Detalles Bibliográficos
Autores principales: Janelle, Valérie, Carli, Cédric, Taillefer, Julie, Orio, Julie, Delisle, Jean-Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413989/
https://www.ncbi.nlm.nih.gov/pubmed/25925868
http://dx.doi.org/10.1186/s12967-015-0495-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413989/
https://www.ncbi.nlm.nih.gov/pubmed/25925868
http://dx.doi.org/10.1186/s12967-015-0495-z

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