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Interleukin-27 re-educates intratumoral myeloid cells and down-regulates stemness genes in non-small cell lung cancer

Current therapies for Non-Small Cell Lung Cancer (NSCLC) still fail to significantly increase its survival rate. Here we asked whether Interleukin(IL)-27, which has revealed powerful antitumor activity and is toxicity-free in humans, is a promising therapeutic choice for NSCLC patients. IL-27's...

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Detalles Bibliográficos
Autores principales: Airoldi, Irma, Tupone, Maria Grazia, Esposito, Silvia, Russo, Marco V., Barbarito, Giulia, Cipollone, Giuseppe, Di Carlo, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414147/
https://www.ncbi.nlm.nih.gov/pubmed/25638163