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NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor

The current standard of care for lung cancer consists of concurrent chemotherapy and radiation. Several studies have shown that the DNA-PKcs inhibitor NU7441 is a highly potent radiosensitizer, however, the mechanism of NU7441's anti-proliferation effect has not been fully elucidated. In this s...

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Detalles Bibliográficos
Autores principales: Yu, Lan, Shang, Zeng-Fu, Hsu, Feng-Ming, Zhang, Zhang, Tumati, Vasu, Lin, Yu-Fen, Chen, Benjamin P.C., Saha, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414158/
https://www.ncbi.nlm.nih.gov/pubmed/25714019