Downregulation of microRNA-23a suppresses prostate cancer metastasis by targeting the PAK6-LIMK1 signaling pathway

Here we found that levels of miR-23a were decreased in prostate cancer cell lines and tumor tissues. These low levels were associated with poor patients' prognosis. MiR-23a inhibited migration and invasion of prostate cancer in vivo and in orthotopic prostate cancer mice model. MiR-23a decrease...

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Detalles Bibliográficos
Autores principales: Cai, Songwang, Chen, Ruihan, Li, Xiaojuan, Cai, Yi, Ye, Zhiqiang, Li, Shigeng, Li, Jun, Huang, Huaiqiu, Peng, Shubin, Wang, Jun, Tao, Yiran, Huang, Hongxing, Wen, Xinglai, Mo, Jianfeng, Deng, Zhupeng, Wang, Jian, Zhang, Yangfan, Gao, Xin, Wen, Xingqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414162/
https://www.ncbi.nlm.nih.gov/pubmed/25714010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414162/
https://www.ncbi.nlm.nih.gov/pubmed/25714010

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