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Identification of NDUFAF1 in mediating K-Ras induced mitochondrial dysfunction by a proteomic screening approach

Increase in aerobic glycolysis and mitochondrial dysfunction are important biochemical features observed in human cancers. Recent studies suggest oncogenic K-Ras can cause suppression of mitochondrial respiration and up-regulation of glycolytic activity through a yet unknown mechanism. Here we emplo...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Song, Ming, Zeng, Zhao-lei, Zhu, Chao-feng, Lu, Wen-hua, Yang, Jing, Ma, Ming-zhe, Huang, A-min, Hu, Yumin, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414165/
https://www.ncbi.nlm.nih.gov/pubmed/25714130