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Artesunate suppresses tumor growth and induces apoptosis through the modulation of multiple oncogenic cascades in a chronic myeloid leukemia xenograft mouse model

Artesunate (ART), a semi-synthetic derivative of artemisinin, is one of the most commonly used anti-malarial drugs. Also, ART possesses anticancer potential albeit through incompletely understood molecular mechanism(s). Here, the effect of ART on various protein kinases, associated gene products, ce...

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Detalles Bibliográficos
Autores principales: Kim, Chulwon, Lee, Jong Hyun, Kim, Sung-Hoon, Sethi, Gautam, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414170/
https://www.ncbi.nlm.nih.gov/pubmed/25738364