Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma

Here we explore the role of the interplay between host immune response and epithelial-mesenchymal-transition (EMT)-Type tumor-budding on the outcome of pancreatic adenocarcinoma (PDAC). CD4+, CD8+, and FOXP3+T-cells as well as iNOS+ (M1) and CD163+-macrophages (M2) were assessed on multipunch tissue...

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Detalles Bibliográficos
Autores principales: Wartenberg, Martin, Zlobec, Inti, Perren, Aurel, Koelzer, Viktor Hendrik, Gloor, Beat, Lugli, Alessandro, Eva, Karamitopoulou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414182/
https://www.ncbi.nlm.nih.gov/pubmed/25669968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414182/
https://www.ncbi.nlm.nih.gov/pubmed/25669968

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