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Progression of naive intraepithelial neoplasia genome to aggressive squamous cell carcinoma genome of uterine cervix

Although cervical intraepithelial neoplasia (CIN) is considered a neoplasia, its genomic alterations remain unknown. For this, we performed whole-exome sequencing and copy number profiling of three CINs, a microinvasive carcinoma (MIC) and four cervical squamous cell carcinomas (CSCC). Both total mu...

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Detalles Bibliográficos
Autores principales: Jung, Seung-Hyun, Choi, Youn Jin, Kim, Min Sung, Baek, In-Pyo, Lee, Sung Hak, Lee, Ah Won, Hur, Soo Young, Kim, Tae-Min, Lee, Sug Hyung, Chung, Yeun-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414197/
https://www.ncbi.nlm.nih.gov/pubmed/25738363