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HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells

Leukemia inhibitory factor (LIF), a multi-functional cytokine, has a complex role in cancer. While LIF induces the differentiation of several myeloid leukemia cells and inhibits their growth, it also promotes tumor progression, metastasis and chemoresistance in many solid tumors. LIF is frequently o...

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Detalles Bibliográficos
Autores principales: Wu, Lihua, Yu, Haiyang, Zhao, Yuhan, Zhang, Cen, Wang, Jiabei, Yue, Xuetian, Yang, Qifeng, Hu, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414199/
https://www.ncbi.nlm.nih.gov/pubmed/25726527