Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy

Oncolytic viruses that selectively replicate in tumor cells can be used for treatment of cancer. Accumulating data suggests that virus induced oncolysis can enhance anti-tumor immunity and break immune tolerance. To capitalize on the immunogenic nature of oncolysis, we generated a quadruple modified...

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Detalles Bibliográficos
Autores principales: Hemminki, Otto, Parviainen, Suvi, Juhila, Juuso, Turkki, Riku, Linder, Nina, Lundin, Johan, Kankainen, Matti, Ristimäki, Ari, Koski, Anniina, Liikanen, Ilkka, Oksanen, Minna, Nettelbeck, Dirk M., Kairemo, Kalevi, Partanen, Kaarina, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414204/
https://www.ncbi.nlm.nih.gov/pubmed/25714011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414204/
https://www.ncbi.nlm.nih.gov/pubmed/25714011

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