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A Human Monoclonal Antibody against Hepatitis B Surface Antigen with Potent Neutralizing Activity

We describe the production and characterization of human monoclonal antibodies (mAb) specific for the major hepatitis B virus (HBV) S protein. The mAbs, two IgG1κ and one IgG1λ, were secreted by B-cell clones obtained from peripheral blood mononuclear cells (PBMC) of one person convalescent from acu...

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Detalles Bibliográficos
Autores principales: Cerino, Antonella, Bremer, Corinna M., Glebe, Dieter, Mondelli, Mario U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414269/
https://www.ncbi.nlm.nih.gov/pubmed/25923526
http://dx.doi.org/10.1371/journal.pone.0125704