Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease

BACKGROUND: Pouchitis is common after ileal pouch-anal anastomosis (IPAA) surgery for ulcerative colitis (UC). Similar to inflammatory bowel disease (IBD), both host genetics and the microbiota are implicated in its pathogenesis. We use the IPAA model of IBD to associate mucosal host gene expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Xochitl C, Kabakchiev, Boyko, Waldron, Levi, Tyler, Andrea D, Tickle, Timothy L, Milgrom, Raquel, Stempak, Joanne M, Gevers, Dirk, Xavier, Ramnik J, Silverberg, Mark S, Huttenhower, Curtis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414286/
https://www.ncbi.nlm.nih.gov/pubmed/25887922
http://dx.doi.org/10.1186/s13059-015-0637-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414286/
https://www.ncbi.nlm.nih.gov/pubmed/25887922
http://dx.doi.org/10.1186/s13059-015-0637-x

Ejemplares similares