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Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer

BACKGROUND: Mammalian target of rapamycin (mTOR) inhibitors have anti-tumor effects against renal cell carcinoma, pancreatic neuroendocrine cancer and breast cancer. In this study, we analyzed the antitumor effects of mTOR inhibitors in small cell lung cancer (SCLC) cells and sought to clarify the m...

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Detalles Bibliográficos
Autores principales: Matsumoto, Masaru, Seike, Masahiro, Noro, Rintaro, Soeno, Chie, Sugano, Teppei, Takeuchi, Susumu, Miyanaga, Akihiko, Kitamura, Kazuhiro, Kubota, Kaoru, Gemma, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414307/
https://www.ncbi.nlm.nih.gov/pubmed/25884680
http://dx.doi.org/10.1186/s12885-015-1202-4