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Osteoarthritis-dependent changes in antinociceptive action of Na(v)1.7 and Na(v)1.8 sodium channel blockers: An in vivo electrophysiological study in the rat

Voltage-gated sodium channel blockers are not traditionally recommended for osteoarthritis (OA) pain therapy, but given the large peripheral drive that follows OA development there is a rationale for their use. Using a rat model of monosodium iodoacetate (MIA)-induced OA we used in vivo electrophysi...

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Detalles Bibliográficos
Autores principales:	Rahman, W., Dickenson, A.H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414363/ https://www.ncbi.nlm.nih.gov/pubmed/25818052 http://dx.doi.org/10.1016/j.neuroscience.2015.03.042

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