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Jagged-1 is required for the expansion of CD4(+) CD25(+) FoxP3(+) regulatory T cells and tolerogenic dendritic cells by murine mesenchymal stromal cells

INTRODUCTION: Mesenchymal stromal cells (MSC) have well defined immunomodulatory properties including the suppression of lymphocyte proliferation and inhibition of dendritic cell (DC) maturation involving both cell contact and soluble factors. These properties have made MSC attractive candidates for...

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Detalles Bibliográficos
Autores principales: Cahill, Emer F, Tobin, Laura M, Carty, Fiona, Mahon, Bernard P, English, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414370/
https://www.ncbi.nlm.nih.gov/pubmed/25890330
http://dx.doi.org/10.1186/s13287-015-0021-5