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Jagged-1 is required for the expansion of CD4(+) CD25(+) FoxP3(+) regulatory T cells and tolerogenic dendritic cells by murine mesenchymal stromal cells
INTRODUCTION: Mesenchymal stromal cells (MSC) have well defined immunomodulatory properties including the suppression of lymphocyte proliferation and inhibition of dendritic cell (DC) maturation involving both cell contact and soluble factors. These properties have made MSC attractive candidates for...
Autores principales: | Cahill, Emer F, Tobin, Laura M, Carty, Fiona, Mahon, Bernard P, English, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414370/ https://www.ncbi.nlm.nih.gov/pubmed/25890330 http://dx.doi.org/10.1186/s13287-015-0021-5 |
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