Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice

Fibrosis refers to the accumulation of excess extracellular matrix (ECM) components and represents a key feature of many chronic inflammatory diseases. Unfortunately, no currently available treatments specifically target this important pathogenic mechanism. MicroRNAs (miRNAs) are short, non-coding R...

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Detalles Bibliográficos
Autores principales: Knabel, Matthew K., Ramachandran, Kalyani, Karhadkar, Sunil, Hwang, Hun-Way, Creamer, Tyler J., Chivukula, Raghu R., Sheikh, Farooq, Clark, K. Reed, Torbenson, Michael, Montgomery, Robert A., Cameron, Andrew M., Mendell, Joshua T., Warren, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414421/
https://www.ncbi.nlm.nih.gov/pubmed/25923107
http://dx.doi.org/10.1371/journal.pone.0124411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414421/
https://www.ncbi.nlm.nih.gov/pubmed/25923107
http://dx.doi.org/10.1371/journal.pone.0124411

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