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Gene expression of OCT4, SOX2, KLF4 and MYC (OSKM) induced pluripotent stem cells: identification for potential mechanisms

BACKGROUND: Somatic cells could be reprogrammed to induced pluripotent stem cells (iPS) by ectopic expression of OCT4, SOX2, KLF4 and MYC (OSKM). We aimed to gain insights into the early mechanisms underlying the induction of pluripotency. METHODS: GSE28688 containing 14 gene expression profiles wer...

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Detalles Bibliográficos
Autores principales: Cai, Yanning, Dai, Xianhua, Zhang, Qianhua, Dai, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414430/
https://www.ncbi.nlm.nih.gov/pubmed/25907774
http://dx.doi.org/10.1186/s13000-015-0263-7