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Alteration of gene expression profile following PPP2R5C knockdown may be associated with proliferation suppression and increased apoptosis of K562 cells

We reported that knockdown of PPP2R5C by siRNA led to proliferation inhibition and apoptosis induction in K562 cells. In this study, we further characterized the gene expression profiles after PPP2R5C suppression by microarray analysis. Genes which participate in the MAPK, PI3K/AKT, and JAK/STAT pat...

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Detalles Bibliográficos
Autores principales: Liu, Sichu, Shen, Qi, Chen, Yu, Zeng, Chengwu, Cao, Changshu, Yang, Lijian, Chen, Shaohua, Wu, Xiuli, Li, Bo, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414434/
https://www.ncbi.nlm.nih.gov/pubmed/25888193
http://dx.doi.org/10.1186/s13045-015-0125-5