Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches

Phosphorylation of the eukaryotic translation initiation factor eIF4E is associated with malignant progression and poor cancer prognosis. Accordingly, here we have analyzed the association between eIF4E phosphorylation and cellular resistance to oxidative stress, starvation, and DNA-damaging agents...

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Detalles Bibliográficos
Autores principales: Martínez, Alba, Sesé, Marta, Losa, Javier Hernandez, Robichaud, Nathaniel, Sonenberg, Nahum, Aasen, Trond, Ramón y Cajal, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414544/
https://www.ncbi.nlm.nih.gov/pubmed/25923732
http://dx.doi.org/10.1371/journal.pone.0123352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414544/
https://www.ncbi.nlm.nih.gov/pubmed/25923732
http://dx.doi.org/10.1371/journal.pone.0123352

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