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Analysis of Gzmb(Cre) as a Model System for Gene Deletion in the Natural Killer Cell Lineage

The analysis of gene function in mature and activated natural killer cells has been hampered by the lack of model systems for Cre-mediated recombination in these cells. Here we have investigated the utility of Gzmb(Cre) for recombination of loxp sequences in these cells predicated on the observation...

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Detalles Bibliográficos
Autores principales: Xu, Yiying, Evaristo, Cesar, Alegre, Maria-Luisa, Gurbuxani, Sandeep, Kee, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414598/
https://www.ncbi.nlm.nih.gov/pubmed/25923440
http://dx.doi.org/10.1371/journal.pone.0125211