Sp1 Mediates a Therapeutic Role of MiR-7a/b in Angiotensin II-Induced Cardiac Fibrosis via Mechanism Involving the TGF-β and MAPKs Pathways in Cardiac Fibroblasts

MicroRNA-7a/b (miR-7a/b) protects cardiac myocytes from apoptosis during ischemia/reperfusion injury; however, its role in angiotensin II (ANG II)-stimulated cardiac fibroblasts (CFs) remains unknown. Therefore, the present study investigated the anti-fibrotic mechanism of miR-7a/b in ANG II-treated...

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Detalles Bibliográficos
Autores principales: Li, Rui, Xiao, Jie, Qing, Xiaoteng, Xing, Junhui, Xia, Yanfei, Qi, Jia, Liu, Xiaojun, Zhang, Sen, Sheng, Xi, Zhang, Xinyu, Ji, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414609/
https://www.ncbi.nlm.nih.gov/pubmed/25923922
http://dx.doi.org/10.1371/journal.pone.0125513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414609/
https://www.ncbi.nlm.nih.gov/pubmed/25923922
http://dx.doi.org/10.1371/journal.pone.0125513

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