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Dysregulation of miR-34a Links Neuronal Development to Genetic Risk Factors for Bipolar Disorder

Bipolar disorder (BD) is a heritable neuropsychiatric disorder with largely unknown pathogenesis. Given their prominent role in brain function and disease, we hypothesized that microRNAs (miRNAs) might be of importance for BD. Here we show that levels of miR-34a, which is predicted to target multipl...

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Detalles Bibliográficos
Autores principales: Bavamian, Sabine, Mellios, Nikolaos, Lalonde, Jasmin, Fass, Daniel M., Wang, Jennifer, Sheridan, Steven D., Madison, Jon M., Zhou, Fen, Rueckert, Erroll H., Barker, Doug, Perlis, Roy H., Sur, Mriganka, Haggarty, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414679/
https://www.ncbi.nlm.nih.gov/pubmed/25623948
http://dx.doi.org/10.1038/mp.2014.176