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Neuronal activity biases axon selection for myelination in vivo

An essential feature of vertebrate neural development is ensheathment of axons with myelin, an insulating membrane formed by oligodendrocytes. Not all axons are myelinated, but mechanisms directing myelination of specific axons are unknown. Using zebrafish we show that activity-dependent secretion s...

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Detalles Bibliográficos
Autores principales: Hines, Jacob H., Ravanelli, Andrew M., Schwindt, Rani, Scott, Ethan K., Appel, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414883/
https://www.ncbi.nlm.nih.gov/pubmed/25849987
http://dx.doi.org/10.1038/nn.3992