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Neuronal activity biases axon selection for myelination in vivo
An essential feature of vertebrate neural development is ensheathment of axons with myelin, an insulating membrane formed by oligodendrocytes. Not all axons are myelinated, but mechanisms directing myelination of specific axons are unknown. Using zebrafish we show that activity-dependent secretion s...
Autores principales: | Hines, Jacob H., Ravanelli, Andrew M., Schwindt, Rani, Scott, Ethan K., Appel, Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414883/ https://www.ncbi.nlm.nih.gov/pubmed/25849987 http://dx.doi.org/10.1038/nn.3992 |
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