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Resolution of the cellular proteome of the nucleocapsid protein from a highly pathogenic isolate of porcine reproductive and respiratory syndrome virus identifies PARP-1 as a cellular target whose interaction is critical for virus biology

Porcine reproductive and respiratory syndrome virus (PRRSV) is a major threat to the swine industry and food security worldwide. The nucleocapsid (N) protein is a major structural protein of PRRSV. The primary function of this protein is to encapsidate the viral RNA genome, and it is also thought to...

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Detalles Bibliográficos
Autores principales: Liu, Long, Lear, Zoe, Hughes, David J., Wu, Weining, Zhou, En-min, Whitehouse, Adrian, Chen, Hongying, Hiscox, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Pub. Co 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414928/
https://www.ncbi.nlm.nih.gov/pubmed/25614100
http://dx.doi.org/10.1016/j.vetmic.2014.11.023