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Improving protein-ligand binding site prediction accuracy by classification of inner pocket points using local features
BACKGROUND: Protein-ligand binding site prediction from a 3D protein structure plays a pivotal role in rational drug design and can be helpful in drug side-effects prediction or elucidation of protein function. Embedded within the binding site detection problem is the problem of pocket ranking – how...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414931/ https://www.ncbi.nlm.nih.gov/pubmed/25932051 http://dx.doi.org/10.1186/s13321-015-0059-5 |