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Double-Strand Breaks from a Radical Commonly Produced by DNA-Damaging Agents

[Image: see text] Double-strand breaks are widely accepted to be the most toxic form of DNA damage. Molecules that produce double-strand breaks via a single chemical event are typically very cytotoxic and far less common than those that form single-strand breaks. It was recently reported that a comm...

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Detalles Bibliográficos
Autores principales: Taverna Porro, Marisa L., Greenberg, Marc M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415041/
https://www.ncbi.nlm.nih.gov/pubmed/25749510
http://dx.doi.org/10.1021/acs.chemrestox.5b00032