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Amyloid β-Protein Assembly: The Effect of Molecular Tweezers CLR01 and CLR03

[Image: see text] The early oligomerization of amyloid β-protein (Aβ) has been shown to be an important event in the pathology of Alzheimer’s disease (AD). Designing small molecule inhibitors targeting Aβ oligomerization is one attractive and promising strategy for AD treatment. Here we used ion mob...

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Detalles Bibliográficos
Autores principales: Zheng, Xueyun, Liu, Deyu, Klärner, Frank-Gerrit, Schrader, Thomas, Bitan, Gal, Bowers, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415044/
https://www.ncbi.nlm.nih.gov/pubmed/25751170
http://dx.doi.org/10.1021/acs.jpcb.5b00692