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Nuclear reprogramming with a non-integrating human RNA virus

INTRODUCTION: Advances in the field of stem cells have led to novel avenues for generating induced pluripotent stem cells (iPSCs) from differentiated somatic cells. iPSCs are typically obtained by the introduction of four factors—OCT4, SOX2, KLF4, and cMYC—via integrating vectors. Here, we report th...

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Detalles Bibliográficos
Autores principales: Driscoll, Christopher B, Tonne, Jason M, El Khatib, Moustafa, Cattaneo, Roberto, Ikeda, Yasuhiro, Devaux, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415226/
https://www.ncbi.nlm.nih.gov/pubmed/25889591
http://dx.doi.org/10.1186/s13287-015-0035-z