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CD27-IgD- memory B cells are modulated by in vivo interleukin-6 receptor (IL-6R) blockade in rheumatoid arthritis

INTRODUCTION: Enhanced B cell activity, particularly memory B cells have gained interest in evaluating response during therapies with biologics. CD27-IgD- double-negative (DN) B cells lacking the conventional memory marker CD27 are reported to be part of the memory compartment, however, only scarce...

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Detalles Bibliográficos
Autores principales: Mahmood, Zafar, Muhammad, Khalid, Schmalzing, Marc, Roll, Petra, Dörner, Thomas, Tony, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415279/
https://www.ncbi.nlm.nih.gov/pubmed/25888920
http://dx.doi.org/10.1186/s13075-015-0580-y