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Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes

Metabolic syndrome and T2D produce significant health and economic issues. Many available animal models have monogenic leptin pathway mutations that are absent in the human population. Development of the ZDSD rat model was undertaken to produce a model that expresses polygenic obesity and diabetes w...

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Detalles Bibliográficos
Autores principales: Peterson, Richard G., Jackson, Charles V., Zimmerman, Karen, de Winter, Willem, Huebert, Norman, Hansen, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415477/
https://www.ncbi.nlm.nih.gov/pubmed/25961053
http://dx.doi.org/10.1155/2015/487816