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Characterization of the Prediabetic State in a Novel Rat Model of Type 2 Diabetes, the ZFDM Rat

We recently established a novel animal model of obese type 2 diabetes (T2D), the Zucker fatty diabetes mellitus (ZFDM) rat strain harboring the fatty mutation (fa) in the leptin receptor gene. Here we performed a phenotypic characterization of the strain, focusing mainly on the prediabetic state. At...

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Detalles Bibliográficos
Autores principales: Gheni, Ghupurjan, Yokoi, Norihide, Beppu, Masayuki, Yamaguchi, Takuro, Hidaka, Shihomi, Kawabata, Ayako, Hoshino, Yoshikazu, Hoshino, Masayuki, Seino, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415487/
https://www.ncbi.nlm.nih.gov/pubmed/25961052
http://dx.doi.org/10.1155/2015/261418