A Novel Approach to Monitor Clearance of Host Cell Proteins Associated With Monoclonal Antibodies

Co-purification of a subset of host cell proteins (HCPs) with monoclonal antibodies (mAbs) during the capture of mAbs on Protein A affinity chromatography is primarily caused by interactions of HCPs with the mAbs. To date, there is limited information about the identity of those HCPs due to the diff...

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Detalles Bibliográficos
Autores principales: Aboulaich, Nabila, Chung, Wai Keen, Thompson, Jenny Heidbrink, Larkin, Christopher, Robbins, David, Zhu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Bioseparations and Downstream Processing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415537/
https://www.ncbi.nlm.nih.gov/pubmed/25044920
http://dx.doi.org/10.1002/btpr.1948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415537/
https://www.ncbi.nlm.nih.gov/pubmed/25044920
http://dx.doi.org/10.1002/btpr.1948

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