Enhanced tethered-flight duration and locomotor activity by overexpression of the human gene SOD1 in Drosophila motorneurons

Mutation of the human gene superoxide dismutase (hSOD1) is associated with the fatal neurodegenerative disease familial amyotrophic lateral sclerosis (Lou Gehrig’s disease). Selective overexpression of hSOD1 in Drosophila motorneurons increases lifespan to 140% of normal. The current study was desig...

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Detalles Bibliográficos
Autores principales: Petrosyan, Agavni, Hsieh, I-Hui, Phillips, John P., Saberi, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2015
Materias:
Cellular, Molecular and Developmental Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415569/
https://www.ncbi.nlm.nih.gov/pubmed/25983632
http://dx.doi.org/10.1590/S1415-475738138120140132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415569/
https://www.ncbi.nlm.nih.gov/pubmed/25983632
http://dx.doi.org/10.1590/S1415-475738138120140132

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