Effect of HDAC Inhibitors on Corneal Keratocyte Mechanical Phenotypes in 3-D Collagen Matrices

PURPOSE: Histone deacetylase inhibitors (HDAC) have been shown to inhibit the TGFβ-induced myofibroblast transformation of corneal fibroblasts in 2-D culture. However, the effect of HDAC inhibitors on keratocyte spreading, contraction, and matrix remodeling in 3-D culture has not been directly asses...

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Detalles Bibliográficos
Autores principales: Koppaka, Vindhya, Lakshman, Neema, Petroll, W. Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415596/
https://www.ncbi.nlm.nih.gov/pubmed/25999677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415596/
https://www.ncbi.nlm.nih.gov/pubmed/25999677

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