IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

Alphaviruses are a group of widely distributed human and animal pathogens. It is well established that their replication is sensitive to type I IFN treatment, but the mechanism of IFN inhibitory function remains poorly understood. Using a new experimental system, we demonstrate that in the presence...

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Detalles Bibliográficos
Autores principales: Reynaud, Josephine M., Kim, Dal Young, Atasheva, Svetlana, Rasalouskaya, Aliaksandra, White, James P., Diamond, Michael S., Weaver, Scott C., Frolova, Elena I., Frolov, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415776/
https://www.ncbi.nlm.nih.gov/pubmed/25927359
http://dx.doi.org/10.1371/journal.ppat.1004863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415776/
https://www.ncbi.nlm.nih.gov/pubmed/25927359
http://dx.doi.org/10.1371/journal.ppat.1004863

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